Cochran R J, Tucker S B, Wilkin J K
Cutis. 1983 Jan;31(1):55-8.
We believe that the disease we are reporting is associated with diabetes, particularly in patients on renal dialysis, and the perforation is initiated by scratching. Decreasing pruritus is the only needed treatment as the lesions tend to resolve on their own. While this entity has been called Kyrle's disease, it more correctly is reactive perforating collagenosis, both clinically and histologically. Whether this is a variant of what Kyrle originally described is not clear. We propose that this entity be called reactive perforating collagenosis of diabetes and renal failure.
我们认为，我们所报告的这种疾病与糖尿病有关，尤其是在接受肾脏透析的患者中，且穿孔是由搔抓引发的。由于病变往往会自行消退，减轻瘙痒是唯一所需的治疗方法。虽然这个实体曾被称为凯尔氏病，但从临床和组织学角度来看，它更确切地应是反应性穿通性胶原病。目前尚不清楚这是否是凯尔最初所描述疾病的一种变体。我们建议将这个实体称为糖尿病和肾衰竭相关性反应性穿通性胶原病。
