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[热应激期间小肠黏膜线粒体的功能状态]

[Functional state of the mitochondria of the small intestine mucosa during heat stress].

作者信息

Musaev Kh N, Rakhimov M M, Almatov K T, Akhmedov R

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1983 Jan;69(1):135-9.

PMID:6825883
Abstract

Rate of respiration and effectiveness of oxidative phosphorylation of intestinal mucosa mitochondria in rats revealed that adaptation to heat loads is accompanied by reversible switching over of the NAD-dependent and succinate ways of mitochondria oxygenation which maintains the normal existence of mucosal cells in conditions of heat stress. Severe heat stress disturbs the functional integrity of the oxygenation switching over and leads to disturbances of the rate of oxygenation and effectiveness of oxidative phosphorylation.

摘要

对大鼠肠黏膜线粒体呼吸速率和氧化磷酸化效率的研究表明,对热负荷的适应伴随着线粒体氧化的NAD依赖途径和琥珀酸途径的可逆转换,这在热应激条件下维持了黏膜细胞的正常存活。严重热应激会扰乱氧化转换的功能完整性,并导致氧化速率和氧化磷酸化效率的紊乱。

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[Functional state of the mitochondria of the small intestine mucosa during heat stress].[热应激期间小肠黏膜线粒体的功能状态]
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