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[不同年龄大鼠小肠线粒体呼吸和氧化磷酸化的空间分布]

[The spatial distribution of mitochondrial respiration and oxidative phosphorylation along the small intestine in rats of different ages].

作者信息

Zaripov B Z, Almatov K T, Kubaev O, Irgashev M S

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1992 Sep;78(9):98-105.

PMID:1338543
Abstract

Growing rats were shown to have the maximum of respiratory and ATP-synthetase activities in the duodenum and proximal part of the small intestine, the minimum--in its distal part, whereas the medial part of the intestinal tube was in intermediate position. These parameters were equally distributed along the small intestine in adult rats. In old rats, the highest rate of oxygen consumption was revealed in the mitochondria of the medial part, the lower one--in the proximal part, and the lowest level was found in the duodenum and in distal part of the small intestine.

摘要

结果表明,生长中的大鼠十二指肠和小肠近端的呼吸和ATP合成酶活性最高,远端最低,而肠管中部处于中间位置。在成年大鼠中,这些参数沿小肠均匀分布。在老年大鼠中,发现线粒体耗氧率最高的部位是肠管中部,其次是近端,十二指肠和小肠远端的耗氧率最低。

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