Classification of DNA polymerase activities from ovaries of the frog, Xenopus laevis.

Four distinct DNA polymerase activities were isolated from ovaries of the frog Xenopus laevis. Specific assays for each activity were established. The isolated activities were characterized by molecular weight, template-primer preferences, and sensitivity to specific inhibitors as Xenopus laevis ovarian DNA polymerases-alpha 1, -alpha 2, -beta, and -gamma. All previously described Xenopus laevis DNA polymerases were classified using these properties.