Talaat M, Gafaar H, Talaat A M, Elwany S
ORL J Otorhinolaryngol Relat Spec. 1983;45(1):20-8. doi: 10.1159/000275622.
The ceruminous glands of the external auditory canal skin of 20 patients suffering from otosclerosis were examined histologically and histochemically. The histological changes included flattening of the lining cells and widening of the lumina of the glands. Histochemical alterations were in the form of diminished succinic dehydrogenase, alpha esterase and alkaline phosphatase enzyme activities. The histological and histochemical changes indicated that atrophy of the ceruminous glands with diminished wax production occurred in some otosclerotic patients. This atrophy may be secondary to the involvement of the ground substance, vessels and nerves of the external auditory canal by the same etiologic factor responsible for the pathogenesis of the otosclerotic process.
对20例耳硬化症患者外耳道皮肤的耵聍腺进行了组织学和组织化学检查。组织学变化包括腺管内衬细胞扁平及腺腔增宽。组织化学改变表现为琥珀酸脱氢酶、α酯酶和碱性磷酸酶活性降低。组织学和组织化学变化表明，部分耳硬化症患者存在耵聍腺萎缩及耵聍分泌减少。这种萎缩可能继发于导致耳硬化过程发病的同一病因对外耳道基质、血管和神经的累及。
