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人外耳道耵聍腺的神经支配。

Human ceruminous gland innervation.

作者信息

Bende M

出版信息

J Laryngol Otol. 1981 Jan;95(1):11-5. doi: 10.1017/s0022215100090344.

DOI:10.1017/s0022215100090344
PMID:7007541
Abstract

Human ceruminous glands have been examined for the presence of adrenergic nerves using the histofluorescence method according to Falck and Hillarp, and immunohistochemistry for the presence of peptidergic nerves. The effect of adrenaline, alpha- and beta-blockers have been tested in vivo. No adrenergic or peptidergic nerves could be seen innervating the ceruminous glands. In spite of that, the glands reacted to local administration of adrenaline. This adrenaline effect could be blocked by alpha-blockers but not by beta-blockers. The cerumnious glands seem to possess alpha-adrenergic receptors, possibly capable of reacting with circulating catecholamines.

摘要

采用法尔克和希拉尔普的组织荧光法检测了人耵聍腺中肾上腺素能神经的存在情况,并通过免疫组织化学检测了肽能神经的存在情况。在体内测试了肾上腺素、α和β受体阻滞剂的作用。未发现有肾上腺素能或肽能神经支配耵聍腺。尽管如此,耵聍腺对局部应用肾上腺素仍有反应。这种肾上腺素效应可被α受体阻滞剂阻断,但不能被β受体阻滞剂阻断。耵聍腺似乎具有α肾上腺素能受体,可能能够与循环中的儿茶酚胺发生反应。

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