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颅内肿瘤中的雌激素和孕激素受体蛋白

Estrogen- and progesterone-receptor proteins in intracranial tumors.

作者信息

Vaquero J, Marcos M L, Martínez R, Bravo G

出版信息

Surg Neurol. 1983 Jan;19(1):11-3. doi: 10.1016/0090-3019(83)90201-x.

DOI:10.1016/0090-3019(83)90201-x
PMID:6828987
Abstract

Estrogen and progesterone receptors have been measured in 13 intracranial tumors (eight meningiomas, two acoustic neurinomas, one primary tumor of neuroectodermal origin, one giant-celled glioblastoma, and one metastasis of carcinoma). Evidence is provided of the presence of progesterone receptors in meningiomas (87.5%). We could not find clear evidence of estrogen receptors in any tumor of this series. Presence of progesterone receptors in meningiomas suggests an explanation for the greater incidence of these tumors in women and their rapid growth during pregnancy.

摘要

对13例颅内肿瘤(8例脑膜瘤、2例听神经瘤、1例神经外胚层起源的原发性肿瘤、1例巨细胞胶质母细胞瘤和1例癌转移瘤)进行了雌激素和孕激素受体检测。有证据表明脑膜瘤中存在孕激素受体(87.5%)。在该系列的任何肿瘤中,我们都未发现雌激素受体的明确证据。脑膜瘤中孕激素受体的存在为这些肿瘤在女性中发病率较高及其在孕期快速生长提供了一种解释。

相似文献

1
Estrogen- and progesterone-receptor proteins in intracranial tumors.颅内肿瘤中的雌激素和孕激素受体蛋白
Surg Neurol. 1983 Jan;19(1):11-3. doi: 10.1016/0090-3019(83)90201-x.
2
[Radioisotopic quantification of hormone receptors in brain tumors and their clinical implications].[脑肿瘤中激素受体的放射性同位素定量分析及其临床意义]
Arch Neurobiol (Madr). 1983 Jul-Aug;46(4):233-42.
3
Estrogen and progesterone receptors in intracranial tumors.颅内肿瘤中的雌激素和孕激素受体
Clin Neuropharmacol. 1984;7(4):338-42. doi: 10.1097/00002826-198412000-00011.
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[Behavior of estrogen and progesterone receptors in intracranial meningioma].[雌激素和孕激素受体在颅内脑膜瘤中的行为]
Pathologica. 1989 Sep-Oct;81(1075):515-22.
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Estrogen and progestin receptors in intracranial tumors.颅内肿瘤中的雌激素和孕激素受体
Horm Res. 1987;27(2):74-7. doi: 10.1159/000180791.
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[Steroid receptors in brain tumors].[脑肿瘤中的类固醇受体]
Minerva Med. 1984 May 19;75(21):1287-92.
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[Estrogen receptors in meningiomas and neurinomas (author's transl)].脑膜瘤和神经鞘瘤中的雌激素受体(作者译)
No To Shinkei. 1982 Apr;34(4):399-404.
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Estrogen and progesterone receptors in meningiomas.脑膜瘤中的雌激素和孕激素受体
J Neurosurg. 1984 May;60(5):985-93. doi: 10.3171/jns.1984.60.5.0985.
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Hormonal steroid receptors in intracranial tumours and their relevance in hormone therapy.颅内肿瘤中的激素甾体受体及其在激素治疗中的相关性。
Eur J Cancer Clin Oncol. 1985 Jun;21(6):711-4. doi: 10.1016/0277-5379(85)90268-8.
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Sex steroid hormone receptors in primary spinal tumors.
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Unique features of pregnancy-related meningiomas: lessons learned from 148 reported cases and theoretical implications of a prolactin modulated pathogenesis.妊娠相关脑膜瘤的独特特征:从148例报告病例中吸取的经验教训及催乳素调节发病机制的理论意义
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Vestibular schwannoma quantitative polymerase chain reaction expression of estrogen and progesterone receptors.
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Laryngoscope. 2008 Aug;118(8):1458-63. doi: 10.1097/MLG.0b013e318177e20b.
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Estrogen receptor beta (ERbeta) is expressed in brain astrocytic tumors and declines with dedifferentiation of the neoplasm.雌激素受体β(ERβ)在脑星形细胞瘤中表达,并随着肿瘤的去分化而下降。
J Cancer Res Clin Oncol. 2004 Jul;130(7):405-10. doi: 10.1007/s00432-004-0548-9.
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Orbital meningiomas: surgery, radiotherapy, or hormones?眼眶脑膜瘤:手术、放疗还是激素治疗?
Br J Ophthalmol. 1993 May;77(5):313-4. doi: 10.1136/bjo.77.5.313.
6
Reproductive factors and risk of brain, colon, and other malignancies in Iowa (United States).美国爱荷华州的生殖因素与脑癌、结肠癌及其他恶性肿瘤的风险
Cancer Causes Control. 1993 Nov;4(6):505-11. doi: 10.1007/BF00052425.
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Cryostat section assay of oestrogen and progesterone receptors in meningiomas: a clinicopathological study.脑膜瘤中雌激素和孕激素受体的冷冻切片测定:一项临床病理研究。
J Clin Pathol. 1986 Jan;39(1):44-50. doi: 10.1136/jcp.39.1.44.
8
Meningiomas in a male fetus from a hormonally dysequilibrated mother.
Childs Nerv Syst. 1985;1(6):359-62. doi: 10.1007/BF00270825.
9
Hormone treatment of meningiomas: lack of response to medroxyprogesterone acetate (MPA). A pilot study of five cases.脑膜瘤的激素治疗:对醋酸甲羟孕酮(MPA)无反应。五例病例的初步研究。
Acta Neurochir (Wien). 1986;80(1-2):35-41. doi: 10.1007/BF01809555.
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Lack of efficacy of megestrol acetate in the treatment of unresectable meningioma.醋酸甲地孕酮治疗不可切除性脑膜瘤无效。
J Neurooncol. 1990 Feb;8(1):61-5. doi: 10.1007/BF00182088.