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催乳素和生长激素对大鼠免疫的调节

Regulation of immunity in rats by lactogenic and growth hormones.

作者信息

Nagy E, Berczi I, Friesen H G

出版信息

Acta Endocrinol (Copenh). 1983 Mar;102(3):351-7. doi: 10.1530/acta.0.1020351.

DOI:10.1530/acta.0.1020351
PMID:6829262
Abstract

Antibody formation to sheep red blood cells and the development of contact dermatitis in response to dinitrochlorobenzene are impaired in hypophysectomized (Hypo-X) rats. Rat prolactin, rat growth hormone, bovine prolactin, bovine growth hormone, human placental lactogen and human growth hormone all restored the immunological competence of Hypo-X animals. The possible mechanism of action of these hormones on immune reactions is discussed.

摘要

垂体切除(Hypo-X)大鼠对绵羊红细胞的抗体形成以及对二硝基氯苯的接触性皮炎反应均受损。大鼠催乳素、大鼠生长激素、牛催乳素、牛生长激素、人胎盘催乳素和人生长激素均可恢复Hypo-X动物的免疫能力。文中讨论了这些激素对免疫反应的可能作用机制。

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