• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

口服硒可抑制无毛小鼠对紫外线的皮肤反应。

Oral selenium inhibits skin reactions to UV light in hairless mice.

作者信息

Thorling E B, Overvad K, Bjerring P

出版信息

Acta Pathol Microbiol Immunol Scand A. 1983 Jan;91(1):81-3. doi: 10.1111/j.1699-0463.1983.tb02730.x.

DOI:10.1111/j.1699-0463.1983.tb02730.x
PMID:6829314
Abstract

In different experimental systems oral selenium has a pronounced anti-carcinogenic effect. This includes both spontaneous and chemically-induced cancers (1, 2, 3, 6, 7, 8). Our primary objective was to study the effect of selenium on the carcinogenic potential of UV light in hairless mice. Fairly early in these experiments, however, it became obvious that the selenium-supplemented mice were considerably more resistant to the acute and sub-acute effects of UV light than were the unsupplemented animals. This was found for the inflammatory reaction as well as for the development of pigmentation. As far as we know, this effect of selenium has not previously been described.

摘要

在不同的实验系统中,口服硒具有显著的抗癌作用。这包括自发癌和化学诱导癌(1, 2, 3, 6, 7, 8)。我们的主要目的是研究硒对无毛小鼠紫外线致癌潜力的影响。然而,在这些实验的早期阶段就很明显,补充硒的小鼠比未补充硒的动物对紫外线的急性和亚急性影响具有更强的抵抗力。这在炎症反应和色素沉着的发展方面都得到了证实。据我们所知,硒的这种作用以前尚未被描述过。

相似文献

1
Oral selenium inhibits skin reactions to UV light in hairless mice.口服硒可抑制无毛小鼠对紫外线的皮肤反应。
Acta Pathol Microbiol Immunol Scand A. 1983 Jan;91(1):81-3. doi: 10.1111/j.1699-0463.1983.tb02730.x.
2
Selenium inhibits UV-light-induced skin carcinogenesis in hairless mice.
Cancer Lett. 1985 Jun;27(2):163-70. doi: 10.1016/0304-3835(85)90105-3.
3
Effects of topical L-selenomethionine with topical and oral vitamin E on pigmentation and skin cancer induced by ultraviolet irradiation in Skh:2 hairless mice.局部应用L-硒代蛋氨酸联合局部及口服维生素E对Skh:2无毛小鼠紫外线照射诱导的色素沉着和皮肤癌的影响。
J Am Acad Dermatol. 2003 Sep;49(3):458-72. doi: 10.1067/s0190-9622(03)00900-9.
4
The effects of topical and oral L-selenomethionine on pigmentation and skin cancer induced by ultraviolet irradiation.局部和口服L-硒代蛋氨酸对紫外线照射诱导的色素沉着和皮肤癌的影响。
Nutr Cancer. 1992;17(2):123-37. doi: 10.1080/01635589209514180.
5
Effects of topical and oral vitamin E on pigmentation and skin cancer induced by ultraviolet irradiation in Skh:2 hairless mice.局部和口服维生素E对Skh:2无毛小鼠紫外线照射诱导的色素沉着和皮肤癌的影响。
Nutr Cancer. 2000;38(1):87-97. doi: 10.1207/S15327914NC381_13.
6
Effect on topical 5-methoxypsoralen on tumorigenesis induced in albino and pigmented hairless mouse skin by UV irradiation.局部应用5-甲氧基补骨脂素对紫外线照射诱导的白化和无毛有色小鼠皮肤肿瘤发生的影响。
J Photochem Photobiol B. 1990 May;5(3-4):343-57. doi: 10.1016/1011-1344(90)85050-7.
7
Chlorpromazine ingestion inhibits UV-induced skin carcinogenesis.
Photochem Photobiol. 1987 Jul;46(1):1-4. doi: 10.1111/j.1751-1097.1987.tb04728.x.
8
Tannins protect against skin tumor promotion induced by ultraviolet-B radiation in hairless mice.单宁可预防无毛小鼠中由紫外线B辐射诱导的皮肤肿瘤促进作用。
Nutr Cancer. 2000;37(1):73-7. doi: 10.1207/S15327914NC3701_9.
9
Inhibitory effect of glycolic acid on ultraviolet-induced skin tumorigenesis in SKH-1 hairless mice and its mechanism of action.乙醇酸对SKH-1无毛小鼠紫外线诱导的皮肤肿瘤发生的抑制作用及其作用机制。
Mol Carcinog. 2001 Jul;31(3):152-60. doi: 10.1002/mc.1050.
10
Sunless skin tanning with dihydroxyacetone delays broad-spectrum ultraviolet photocarcinogenesis in hairless mice.使用二羟基丙酮进行的无阳光皮肤晒黑可延缓无毛小鼠的广谱紫外线光致癌作用。
Mutat Res. 2003 Dec 9;542(1-2):129-38. doi: 10.1016/j.mrgentox.2003.09.003.

引用本文的文献

1
Antioxidant capacities of the selenium nanoparticles stabilized by chitosan.壳聚糖稳定的硒纳米颗粒的抗氧化能力。
J Nanobiotechnology. 2017 Jan 5;15(1):4. doi: 10.1186/s12951-016-0243-4.