Standards for treatment of primary and secondary syphilis.

A total of 4.8 million u of benzathine penicillin G was used to treat 500 patients with their first attack of primary syphilis and 522 with secondary syphilis. All patients with primary syphilis became seronegative within one year, and those with secondary syphilis within two years. The physician now has an objective norm in evaluating the effect of treatment in patients with their first attack of primary or secondary syphilis.