Thurnau G R, Tamura R K, Sabbagha R, Depp O R, Dyer A, Larkin R, Lee T, Laughlin C
Am J Obstet Gynecol. 1983 Mar 1;145(5):557-61. doi: 10.1016/0002-9378(83)91195-x.
Based on ultrasonographic mensuration, a number of equations have previously been devised for the purpose of estimating fetal weights. The objective of this study was to develop a mathematical equation that is simple, accurate, and easy to use when applied to preterm or low-birth weight fetuses (less than 2,500 gm). Real-time ultrasound measurements of fetal biparietal diameters (BPDs) and abdominal circumferences (ACs) were obtained in 62 pregnant women within one week of premature delivery. Mean gestational age and mean birth weight +/- SD for this study group of neonates were 28.5 +/- 3.5 weeks and 1,135 +/- 343 gm, respectively. With the aid of computer analysis, a simple regression equation was derived: EFW = (BPD x AC x 9.337) - 229. When predicted estimated fetal weight (EFW) was compared with actual birth weight (ABW), multiple regression analysis demonstrated a correlation coefficient (R) of 0.957. Preliminary results on 19 patients of a prospective study showed an absolute mean difference between the computed EFWs and the ABWs to be within 7.0% of ABW (70 gm/kg of ABW). The standard deviation of the difference was 9.3% of ABW (93 gm/kg of ABW). Based on these data, this simple equation appears to be clinically reliable and easy to use when estimating weights of preterm or low-birth weight fetuses of less than 2,500 gm.
基于超声测量,此前已设计出一些用于估算胎儿体重的公式。本研究的目的是开发一个数学公式,该公式在应用于早产或低出生体重胎儿(小于2500克)时简单、准确且易于使用。在62名孕妇早产前一周内获取胎儿双顶径(BPD)和腹围(AC)的实时超声测量值。该研究组新生儿的平均胎龄和平均出生体重±标准差分别为28.5±3.5周和1135±343克。借助计算机分析,得出一个简单回归方程:估计胎儿体重(EFW)=(双顶径×腹围×9.337)-229。当将预测的估计胎儿体重(EFW)与实际出生体重(ABW)进行比较时,多元回归分析显示相关系数(R)为0.957。一项前瞻性研究中19名患者的初步结果显示,计算得出的估计胎儿体重与实际出生体重之间的绝对平均差异在实际出生体重的7.0%以内(每千克实际出生体重相差70克)。差异的标准差为实际出生体重的9.3%(每千克实际出生体重相差93克)。基于这些数据,这个简单公式在估算体重小于2500克的早产或低出生体重胎儿体重时,似乎在临床上是可靠且易于使用的。