Hamill R, Oney L A, Crane L R
Arch Intern Med. 1983 Mar;143(3):581-3.
A case of extensive rhinocerebral mucormycosis, with associated bilateral brain abscesses, occurred in a man with diabetes. A Rhizopus sp grew from the initial nasal biopsy specimens. Successful therapy consisted of correcting metabolic acidosis, using serial computed tomographic (CT) scans to follow the progressive course of brain involvement from cerebritis to encapsulated abscesses, and performing successive biopsies to determine the adequacy of treatment. On 18-month follow-up, the patient had returned to full-time employment with minimal neurologic impairment. With CT scanning and aggressive therapy, rhinocerebral mucormycosis with bilateral brain involvement can be cured.
一名糖尿病男性患者发生了一例广泛的鼻脑毛霉菌病，并伴有双侧脑脓肿。从最初的鼻腔活检标本中培养出了根霉菌。成功的治疗包括纠正代谢性酸中毒，使用系列计算机断层扫描（CT）来跟踪脑受累从脑炎到包膜脓肿的进展过程，并进行连续活检以确定治疗的充分性。在18个月的随访中，患者已恢复全职工作，神经功能损害最小。通过CT扫描和积极治疗，双侧脑受累的鼻脑毛霉菌病可以治愈。
