Meltzer R S, Diebold B, Valk N K, Blanchard D, Guermonprez J L, Lancée C T, Peronneau P, Roelandt J
Br Heart J. 1983 Mar;49(3):244-9. doi: 10.1136/hrt.49.3.244.
The slope of an individual contrast trajectory on M-mode contrast echocardiography represents a physiological variable similar to that measured by Doppler echocardiography: the projection of the intracardiac velocity vector in the direction of the sound beam. To test the hypothesis that M-mode contrast echocardiography slope measurement can yield information quantitatively similar to Doppler measurements, we performed both simultaneously in 11 normal volunteers. A pulsed Doppler unit capable of simultaneous M-mode and Doppler display was used. Contrast was obtained by intravenous injection of 5% dextrose. Two independent observers measured velocity simultaneously by both techniques at eight to 16 points per subject. One observer repeated the measurements a month later. All subjects had contrast, and 10 had sufficient quality tracings for simultaneous Doppler and contrast slope measurements. The correlation between velocity measurements by both techniques was good, though velocities by Doppler echocardiography were less than by M-mode contrast echocardiography. We conclude that the component of flow velocity towards or away from the transducer can be measured from M-mode contrast trajectory slopes as well as by Doppler echocardiography. M-mode contrast echocardiography may provide a practical method for verifying or calibrating Doppler measurements in vivo.
M 型对比超声心动图上个体对比轨迹的斜率代表了一个与多普勒超声心动图测量的生理变量相似的变量：心腔内速度矢量在声束方向上的投影。为了检验 M 型对比超声心动图斜率测量能够产生与多普勒测量在数量上相似信息的假设，我们在 11 名正常志愿者中同时进行了这两种测量。使用了一台能够同时进行 M 型和多普勒显示的脉冲多普勒仪。通过静脉注射 5%葡萄糖获得对比剂。两名独立观察者通过两种技术在每个受试者的 8 至 16 个点同时测量速度。一名观察者在一个月后重复测量。所有受试者都有对比剂，10 名受试者有足够质量的描记图用于同时进行多普勒和对比斜率测量。尽管多普勒超声心动图测量的速度低于 M 型对比超声心动图测量的速度，但两种技术测量速度之间的相关性良好。我们得出结论，朝向或远离换能器的流速分量既可以通过 M 型对比轨迹斜率测量，也可以通过多普勒超声心动图测量。M 型对比超声心动图可能为体内验证或校准多普勒测量提供一种实用方法。
