Morita H, Mizushige K, Ohmori K, Senda S, Nakajima S, Fukada H, Matsuo H
Second Department of Internal Medicine, Kagawa Medical School.
J Cardiol. 1990;20(2):447-56.
Conventional single-beam pulsed Doppler echocardiography has certain limitations in quantitatively measuring the intracardiac blood flow, because the Doppler incident-angle to the flow stream is uncertain. In the present study, the absolute velocity and direction of the intracardiac blood flow, i.e., flow vector, were measured using our newly-developed dual-frequency two-beam pulsed Doppler echocardiography. This instrument has two transducers with center frequencies of 3.5 MHz (main-beam) and 2.2 MHz (sub-beam) which are linked by two arms. Three potentiometers are set up by the three joints to sense the relative angles. Two velocity components at the intersection of the main- and sub-Doppler beams were measured simultaneously with different directional approaches. The flow vector was calculated manually from the two velocity components. The study population consisted of 18 healthy subjects ranging in age from 23 to 39 years. The left ventricular (LV) inflow vector was measured at the center of the mitral annulus, and the ejection flow vector was measured at the levels of the tip (E1) and the mid-portion (E2) of the anterior mitral leaflet in the LV outflow tract. The results were as follows: 1. The LV rapid inflow (R) was directed slight posteriorly towards the cardiac apex, and its average maximal velocity was 78 +/- 15 cm/sec (mean +/- SD). The LV inflow due to the atrial contraction was directed even more posteriorly than was the R, and its average maximum velocity was 43 +/- 10 cm/sec. 2. The LV ejection flows at E1 and E2 were directed slightly posteriorly rather than parallel to the interventricular septum, and the maximum velocity at E1 and E2 was 53 +/- 20 m/sec and 85 +/- 23 cm/sec, respectively. In conclusion, the dual-frequency two-beam pulsed Doppler technique allows quantitative measurement of the intracardiac blood flow dynamics regardless of the Doppler incident-angle to the flow stream.
传统的单束脉冲多普勒超声心动图在定量测量心腔内血流方面存在一定局限性,因为多普勒波束与血流方向的夹角不确定。在本研究中,我们使用新开发的双频双束脉冲多普勒超声心动图测量心腔内血流的绝对速度和方向,即血流矢量。该仪器有两个换能器,中心频率分别为3.5MHz(主波束)和2.2MHz(子波束),通过两个臂连接。三个关节处设置了三个电位器以感知相对角度。通过不同的方向测量方法同时测量主、子多普勒波束交点处的两个速度分量。根据这两个速度分量手动计算出血流矢量。研究对象为18名年龄在23至39岁之间的健康受试者。在二尖瓣环中心测量左心室(LV)流入矢量,在左心室流出道二尖瓣前叶尖端(E1)和中部(E2)水平测量射血血流矢量。结果如下:1.左心室快速充盈(R)方向略向后指向心尖,其平均最大速度为78±15cm/秒(平均值±标准差)。心房收缩引起的左心室流入方向比R更向后,其平均最大速度为43±10cm/秒。2.在E1和E2处的左心室射血血流方向略向后,而不是与室间隔平行,E1和E2处的最大速度分别为53±20cm/秒和85±23cm/秒。总之,双频双束脉冲多普勒技术能够定量测量心腔内血流动力学,而不受多普勒波束与血流方向夹角的影响。