Coryell W, Zimmerman M
Biol Psychiatry. 1983 Jan;18(1):21-7.
In an earlier report, the dexamethasone suppression test (DST) predicted globally rated outcome at discharge in 42 patients treated with ECT. To determine the predictive value of the DST following discharge we reevaluated these patients 6 months after admission. Suppressors and nonsuppressors did not differ in any of the follow-up measures; DST results added very little to the variance accounted for by diagnosis, age, and episode duration. Surprisingly, patients whose DST had converted at discharge from abnormal to normal were less likely to have sustained remission during follow-up than were patients whose DST had remained abnormal.
在一份较早的报告中,地塞米松抑制试验(DST)预测了42例接受电休克治疗(ECT)患者出院时的整体评定结果。为了确定出院后DST的预测价值,我们在患者入院6个月后对其进行了重新评估。抑制者和非抑制者在任何一项随访指标上均无差异;DST结果对由诊断、年龄和发作持续时间所解释的方差增加甚少。令人惊讶的是,与DST仍异常的患者相比,那些DST在出院时从异常转为正常的患者在随访期间持续缓解的可能性较小。