[关节炎支原体对大鼠淋巴细胞的促有丝分裂作用]
[Mitogenic action of Mycoplasma arthritidis on the lymphoid cells of rats].
作者信息
Pronin A V, Khorobrykh V V
出版信息
Biull Eksp Biol Med. 1983 Apr;95(4):89-91.
PMID:6831028
Abstract
Proliferation of rat splenocytes was studied under the conditions of Mycoplasma infection in vitro. M. arthritidis in doses less than 10(7) CFU/ml exhibited a mitogenic action which seemed likely to be associated with Mycoplasma-produced factor. In higher doses M. arthritidis suppressed blast transformation caused by non-specific mitogens.
摘要
在体外支原体感染的条件下研究了大鼠脾细胞的增殖情况。剂量小于10⁷CFU/ml的关节炎支原体表现出促有丝分裂作用，这似乎可能与支原体产生的因子有关。在较高剂量时，关节炎支原体抑制了由非特异性有丝分裂原引起的母细胞转化。
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