Crawford B E, Stromeyer F W
Cancer. 1983 May 1;51(9):1760-3. doi: 10.1002/1097-0142(19830501)51:9<1760::aid-cncr2820510933>3.0.co;2-n.
Two small carcinomas of the colon were examined, one an intramucosal carcinoma and the other a small carcinoma invading the submucosa. Serial sections did not reveal any adenomatous hyperplasia or polyps in the vicinity. The colonoscopist must be aware of the potential clinical importance of any small mucosal excrescence. Although several studies have indicated that most colonic carcinomas develop from an adenomatous polyp, some carcinomas apparently arise de novo. Further study of the epidemiologic, etiologic, and prognostic factors relating to these apparently uncommon lesions is indicated.
对两个结肠小癌进行了检查，一个是黏膜内癌，另一个是侵犯黏膜下层的小癌。连续切片未发现附近有任何腺瘤样增生或息肉。结肠镜检查医师必须意识到任何小的黏膜赘生物潜在的临床重要性。尽管多项研究表明大多数结肠癌由腺瘤样息肉发展而来，但一些癌显然是新发的。有必要对与这些明显不常见病变相关的流行病学、病因学和预后因素进行进一步研究。
