Laskin W B, James L P
Hum Pathol. 1983 Jan;14(1):83-5. doi: 10.1016/s0046-8177(83)80050-1.
This case report describes an occult papillary adenocarcinoma of the thyroid with pulmonary metastases, discovered at autopsy. Since papillary adenocarcinoma of the thyroid usually invades adjacent structures and cervical lymph nodes in a predictable fashion, the finding of distant hematogenous spread, when the tumor is confined to the thyroid gland, is unusual, as is illustrated by a review of the literature. The patient's history included a poorly differentiated squamous cell carcinoma of the lung, which had been resected 15 years prior to death and had been followed by super-voltage radiation. The possible effects of super-voltage radiation on the pathogenesis and behavior of thyroid cancer are discussed.
本病例报告描述了一例经尸检发现的隐匿性甲状腺乳头状腺癌伴肺转移。由于甲状腺乳头状腺癌通常以可预测的方式侵犯相邻结构和颈部淋巴结，因此当肿瘤局限于甲状腺时出现远处血行转移的情况并不常见，文献回顾也证实了这一点。患者既往有肺低分化鳞状细胞癌病史，该肿瘤在患者死亡前15年已切除，并接受了超高压放疗。本文讨论了超高压放疗对甲状腺癌发病机制和行为的可能影响。
