Tadanier J, Hallas R, Holms J, Freiberg L A, Bacino D
J Antibiot (Tokyo). 1983 Mar;36(3):267-75. doi: 10.7164/antibiotics.36.267.
Selective reactions of 3-O-demethyl-3-O-methanesulfonyl-4-N, 5-O-methylenefortimicin derivatives have been used as the key steps in the syntheses of 3-amino-3-demethoxyfortimicin A and the C-2 epimeric 2-amino-3-O-demethyl-2-deoxyfortimicins A. In vitro antibacterial activities of the new fortimicin derivatives are reported.
