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使用不同公式估算肝肿瘤体积——大鼠实验研究

Estimation of liver tumor volume using different formulas - an experimental study in rats.

作者信息

Carlsson G, Gullberg B, Hafström L

出版信息

J Cancer Res Clin Oncol. 1983;105(1):20-3. doi: 10.1007/BF00391826.

Abstract

Experimental solitary ellipsoid liver tumors in the rat can be induced by inoculation of a tumor-cell suspension of known potency into the liver parenchyma. During laparotomy, the largest (a) and the smallest (b) superficial diameters of the tumor were measured on the surface of the liver with vernier calipers. Four different formulas have been tested and compared with the actual volume from the extirpated tumor and tumor weight. Within the size range of 15-700 mm3, based on the calculation of the difference between logarithmic tumor volume from the different formulas versus logarithmic volume of extirpated and dissected tumors and regression analyses, volume of the unremoved liver tumor can be best calculated according to the formula V = a x b2/2.

摘要

通过将已知效力的肿瘤细胞悬液接种到大鼠肝脏实质中,可以诱导出实验性孤立性椭圆形肝肿瘤。在剖腹手术期间,用游标卡尺在肝脏表面测量肿瘤的最大(a)和最小(b)表面直径。已经测试了四种不同的公式,并将其与切除肿瘤的实际体积和肿瘤重量进行了比较。在15 - 700 mm³的大小范围内,基于对不同公式计算的对数肿瘤体积与切除和解剖肿瘤的对数体积之间差异的计算以及回归分析,未切除的肝肿瘤体积可以根据公式V = a x b²/2进行最佳计算。

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