Takagi T, Chung T G, Saito A
J Chromatogr. 1983 Feb 11;272(2):279-85. doi: 10.1016/s0378-4347(00)86130-7.
The levels of putrescine, cadaverine, spermidine and spermine in uremic plasma were determined with an automatic polyamine analyzer with a 7.5 X 0.2 cm I.D. cation-exchange column using a stepwise sodium chloride gradient. All four polyamines were higher in ten patients with chronic renal failure than in eight normal subjects. The total polyamine content was also measured in the patients' plasma before and after maintenance dialysis; putrescine and spermidine levels were significantly lowered by the procedure.
使用内径为7.5×0.2厘米的阳离子交换柱，通过逐步氯化钠梯度洗脱，用自动多胺分析仪测定尿毒症血浆中腐胺、尸胺、亚精胺和精胺的水平。十名慢性肾衰竭患者的所有四种多胺水平均高于八名正常受试者。还测量了维持性透析前后患者血浆中的总多胺含量；该操作使腐胺和亚精胺水平显著降低。
