Recent advances in the treatment of psoriasis.

Because psoriasis is a disease of unknown etiology, all treatments are based on empirical experience and diverse scientific theories. Although there is no present cure for psoriasis, many forms of therapy are effective in control of the disorder. These range from topical medications such as tar, anthralin, corticosteroids; phototherapy and photochemotherapy; systemic medication, including cytotoxic agents; and vitamin A analogues or retinoids. This report focuses on modifications of existing therapies based on advances in basic science knowledge and technology, combination therapies, as well as new therapeutic agents and new approaches to the treatment of psoriasis.