女性膀胱三角区鳞状化生的连接模式。一项冷冻蚀刻研究。

Junctional pattern in the squamous metaplasia of the female trigone. A freeze-fracture study.

作者信息

Sideri M, De Virgiliis G, Rainoldi R, Ferrari A, Remotti G

出版信息

J Urol. 1983 Feb;129(2):280-3. doi: 10.1016/s0022-5347(17)52050-9.

DOI:10.1016/s0022-5347(17)52050-9

Abstract

The junctional pattern of squamous metaplasia in the female trigone was studied by the freeze-fracture technique. Desmosomes were observed in all epithelial layers and varied in complexity from the basal to the superficial layers. Gap junctions were observed in the lower and upper epithelial layers. Tight junctions were detected occasionally in the superficial layer only, which appeared as maculae and did not form zonulae occludens. These data support previous suggestions that the squamous metaplastic epithelium is not waterproof and may interfere with the contraction-expansion mechanism of the bladder.

摘要

采用冷冻蚀刻技术研究了女性膀胱三角区鳞状化生的连接模式。在所有上皮层均观察到桥粒，其复杂性从基底层到表层有所不同。在上皮的下层和上层观察到缝隙连接。紧密连接仅偶尔在表层检测到，呈斑状，未形成封闭小带。这些数据支持了先前的观点，即鳞状化生上皮不防水，可能会干扰膀胱的收缩-扩张机制。