Logan K R, Hopwood D, Milne G
J Pathol. 1978 Nov;126(3):157-63. doi: 10.1002/path.1711260304.
The appearances of this intercellular junctions in normal and in inflamed oesophageal epithelium are described. Typical hemidesmosomes occur along the abluminat aspect of the basal cells. Desmosomes are most frequent in the prickle cell layer, where desmosome fields may occur, and in the lower functional cell layer. Their fate in the upper layers is not known. Gap junctions are few in the basal cell layer and rare in the most superficial layers. They are maximal in the prickle cell layer. Tight junctions only occur in inflamed tissue between the most superficial cells usually as part of a lateral intercellular junctional complex that also contains belt desmosomes. They may represent attempts by a non-keratinised epithelium to increase its defences against toxic luminal contents.
本文描述了正常和炎症状态下食管上皮细胞间连接的外观。典型的半桥粒沿基底细胞的无腔面分布。桥粒在棘细胞层最为常见，在该层可能出现桥粒区，在较低的功能细胞层也较为常见。它们在上层的情况尚不清楚。缝隙连接在基底细胞层较少，在最表层罕见。在棘细胞层数量最多。紧密连接仅出现在炎症组织中最表层细胞之间，通常是横向细胞间连接复合体的一部分，该复合体还包含带状桥粒。它们可能代表未角化上皮为增强对有毒管腔内容物的防御而做出的尝试。
