Blakemore W F
Neuropathol Appl Neurobiol. 1978 Jan-Feb;4(1):47-59. doi: 10.1111/j.1365-2990.1978.tb00528.x.
The extent and type of remyelination that occurred following demyelination induced by intraspinal injection of small volumes of lysolecithin was examined in 24 rabbits. Unlike the rat and cat following this procedure remyelination is not complete even after 6 months' survival and little Schwann cell invasion occurs. The cellular environment around remyelinated and persistently demyelinated axons differed. Remyelination was associated with a good astrocytic presence and removal of myelin debris, while persistently demyelinated axons were surrounded by myelin debris and a poor astrocytic presence. It was conluded that the environment around the demyelinated axon influences oligodendrocyte remyelination.
对24只兔子进行了研究，以检查脊髓内注射少量溶血卵磷脂诱导脱髓鞘后发生的再髓鞘化的程度和类型。与大鼠和猫在该操作后的情况不同，即使存活6个月后，再髓鞘化也不完全，且几乎没有施万细胞侵入。再髓鞘化轴突和持续脱髓鞘轴突周围的细胞环境不同。再髓鞘化与良好的星形胶质细胞存在及髓磷脂碎片清除有关，而持续脱髓鞘轴突则被髓磷脂碎片包围且星形胶质细胞存在较少。得出的结论是，脱髓鞘轴突周围的环境影响少突胶质细胞的再髓鞘化。
