McDonald M W, Diokno A C, Seski J C, Menon K M
J Surg Oncol. 1983 Mar;22(3):164-6. doi: 10.1002/jso.2930220305.
Progesterone receptor was measured in eight samples of renal cell carcinoma, nine samples of normal renal tissue, and one sample of melanoma tissue. Progesterone receptor was identified in all samples, with the exception of one renal cell carcinoma. Three patients, all with receptor-positive tumors, were treated with medroxyprogesterone acetate for metastatic disease. In one of these patients there was a partial objective response to treatment. Further research regarding progesterone receptor in renal cell carcinoma is indicated.
对8份肾细胞癌样本、9份正常肾组织样本和1份黑色素瘤组织样本进行了孕激素受体检测。除1份肾细胞癌样本外，所有样本均检测到孕激素受体。3例患者的肿瘤均为受体阳性，均接受醋酸甲羟孕酮治疗转移性疾病。其中1例患者对治疗有部分客观反应。表明需要对肾细胞癌中的孕激素受体进行进一步研究。
