Karr J P, Pontes J E, Schneider S, Sandberg A A, Murphy G P
J Surg Oncol. 1983 Jun;23(2):117-24. doi: 10.1002/jso.2930230216.
A review of the role of steroid hormone receptors and hormonal dependence of renal cell carcinoma in certain patients is presented. The results of a cumulative series of estrogen, progesterone, and androgen receptor assays performed on 48 normal and malignant human renal tumor specimens are given. The detectable presence of receptor proteins in certain patients could obviate the empirical use of hormonal therapy, an issue that may be resolved through a randomized multiinstitutional trial.
本文综述了类固醇激素受体的作用以及某些患者肾细胞癌的激素依赖性。给出了对48例正常和恶性人肾肿瘤标本进行的一系列雌激素、孕激素和雄激素受体检测的累积结果。某些患者中可检测到受体蛋白的存在可能避免激素治疗的经验性使用，这一问题可通过多机构随机试验来解决。
