Connolly D C, Elveback L R, Oxman H A
Mayo Clin Proc. 1983 Apr;58(4):249-54.
The data in this blood pressure study were obtained from 1,069 patients who had their first manifestation of coronary artery disease during the 16-year period 1960 through 1975. Case fatality rates (death within 30 days) were least in the normotensive and treated hypertensive patients with myocardial infarction and greatest in the untreated hypertensive patients. Women were less likely than men to acquire coronary artery disease, but a higher proportion of women with coronary artery disease had hypertension. Patients with definite hypertension were older than those with borderline hypertension, and patients with borderline hypertension were older than normotensive patients with coronary artery disease. The data demonstrate that hypertension is a prognostic factor of serious significance in patients who have symptomatic coronary artery disease, and the prognostic significance of borderline hypertension is almost as serious as that of definite hypertension in these patients. Treatment improved survival in patients with definite hypertension, and adequate treatment improved survival to a greater degree than did inadequate treatment.
这项血压研究的数据来自于1960年至1975年这16年间首次出现冠状动脉疾病症状的1069名患者。心肌梗死患者中，血压正常和接受治疗的高血压患者的30天病死率最低，未接受治疗的高血压患者的30天病死率最高。女性患冠状动脉疾病的可能性低于男性，但患冠状动脉疾病的女性中高血压患者的比例更高。确诊高血压患者比临界高血压患者年龄大，临界高血压患者比患有冠状动脉疾病的血压正常患者年龄大。数据表明，高血压是有症状的冠状动脉疾病患者的一个具有严重意义的预后因素，在这些患者中，临界高血压的预后意义几乎与确诊高血压一样严重。治疗可提高确诊高血压患者的生存率，充分治疗比不充分治疗能更大程度地提高生存率。
