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O6-methylguanine, but not N7-methylguanine or N3-methyladenine, induces gene mutations, sister-chromatid exchanges and chromosomal aberrations in Chinese hamster cells.

作者信息

Kaina B, Heindorff K, Aurich O

出版信息

Mutat Res. 1983 Mar;108(1-3):279-92. doi: 10.1016/0027-5107(83)90126-4.

DOI:10.1016/0027-5107(83)90126-4
PMID:6835224
Abstract
摘要

相似文献

1
O6-methylguanine, but not N7-methylguanine or N3-methyladenine, induces gene mutations, sister-chromatid exchanges and chromosomal aberrations in Chinese hamster cells.O6-甲基鸟嘌呤而非N7-甲基鸟嘌呤或N3-甲基腺嘌呤，可诱导中国仓鼠细胞发生基因突变、姐妹染色单体交换和染色体畸变。
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2
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Evidence that sister chromatid exchanges and chromatid breaks are two independent events.姐妹染色单体交换和染色单体断裂是两个独立事件的证据。
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Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models.Mex-、Mex+ 和甲基化耐受错配修复受损细胞中由 O6-甲基鸟嘌呤诱导的染色体不稳定、生殖细胞死亡和凋亡：事实与模型
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Chromosomal effects of sodium selenite in vivo. III. Aberrations and sister chromatid exchanges in Chinese hamster bone marrow.亚硒酸钠在体内的染色体效应。III. 中国仓鼠骨髓中的畸变和姐妹染色单体交换
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Sister-chromatid exchange and chromosomal aberration induction in cultured Chinese hamster cells by the monomethylbenz[a]anthracenes.
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Toxicological Properties of 7-Methylguanine, and Preliminary Data on its Anticancer Activity.7-甲基鸟嘌呤的毒理学特性及其抗癌活性的初步数据。
Front Pharmacol. 2022 Jul 6;13:842316. doi: 10.3389/fphar.2022.842316. eCollection 2022.
2
Understanding the importance of low-molecular weight (ethylene oxide- and propylene oxide-induced) DNA adducts and mutations in risk assessment: Insights from 15 years of research and collaborative discussions.了解低分子量（环氧乙烷和环氧丙烷诱导的）DNA加合物及突变在风险评估中的重要性：来自15年研究与合作讨论的见解
Environ Mol Mutagen. 2019 Mar;60(2):100-121. doi: 10.1002/em.22248. Epub 2018 Dec 10.
3
Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.
突变型单纯疱疹病毒DNA聚合酶降低体内诱变作用涉及改善核苷酸选择。
Proc Natl Acad Sci U S A. 1985 Jun;82(11):3889-93. doi: 10.1073/pnas.82.11.3889.