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瑞典新生儿群体在产前和围产期状况下最优性降低。

Reduced optimality in pre- and perinatal conditions in a Swedish newborn population.

作者信息

Kyllerman M, Hagberg G

出版信息

Neuropediatrics. 1983 Feb;14(1):37-42. doi: 10.1055/s-2008-1059550.

DOI:10.1055/s-2008-1059550
PMID:6835481
Abstract

The optimality concept of Prechtl was adopted for the investigation of a series of 229 newborn infants, selected by paired sampling as controls to 116 dyskinetic cerebral palsy cases. A list of 34 conditions, subgrouped into 14 prepartum, 10 partum and 10 postpartum items, was designed and criterias for optimality were defined. When a condition fell short of criteria for optimality, the infant concerned was given a non-optimal point. The sum of non-optimal points for each infant was defined as the reduced optimality score and the proportion of non-optimal points as the reduced optimality rate. The self-weighting capacity of the reduced optimality score system was confirmed. Lack of optimality compared to optimality in a particular item was generally related to a significant increase of the reduced optimality rates of remaining items. Reduced optimality compared to optimality was in the prepartum period significantly more often followed by reduced optimality than optimality in the partum and postpartum periods. In clinical categories--preterm birth, low birth weight, small for gestational age, and combinations of these--a significant increase of the reduced optimality rates were found. Outcome in items comparable to vital statistics were all close to the expected. The series was considered representative for Swedish children born during the period from 1959-70.

摘要

采用普雷赫特尔的最优性概念,对229名新生儿进行了调查,这些新生儿是通过配对抽样选取的,作为116例运动障碍型脑瘫病例的对照。设计了一份包含34项情况的清单,分为14项产前、10项产时和10项产后项目,并定义了最优性标准。当一种情况不符合最优性标准时,相关婴儿会被给予一个非最优分数。每个婴儿的非最优分数总和被定义为降低的最优性得分,非最优分数的比例被定义为降低的最优性率。降低的最优性得分系统的自加权能力得到了证实。与某一特定项目的最优性相比,缺乏最优性通常与其余项目降低的最优性率显著增加有关。与最优性相比,产前阶段降低的最优性之后更常出现降低的最优性,而不是产时和产后阶段的最优性。在临床类别——早产、低出生体重、小于胎龄以及这些情况的组合——中,发现降低的最优性率显著增加。与生命统计数据可比项目的结果均接近预期。该系列被认为代表了1959年至1970年期间在瑞典出生的儿童。

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