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[焦虑及其不同形式躯体化的新型长效治疗方法:低剂量氟司必林]

[New long-acting treatment of anxiety and its different forms of somatization: low-dose fluspirilene].

作者信息

Giannelli A, Zarattini F

出版信息

Minerva Med. 1983 Mar 31;74(13):727-33.

PMID:6835561
Abstract

After pharmacological considerations on fluspirilene, a diphenylbutylpiperidinic neuroleptic with a tranquillizing action in neurotic syndromes, the Authors refer on 24 patients with a normal social behaviour treated with low dosage. I.M. weekly dosages of 1.5 mg have been used for 6 weeks with semi-quantitative evaluation of 1-5 psychic items, 10 neurovegetative items and 36 miscellaneous. A significant improvement was obtained for nearly all symptoms and did not cause variations in bodyweight, pressure values and pulse frequency or local or systemic intolerance. Positive results reached 77.3% of treated cases, in agreement with those reported by numerous foreign Authors.

摘要

在对氟斯必林进行药理学考量后(氟斯必林是一种二苯基丁基哌啶类抗精神病药物,对神经症综合征有镇静作用),作者提及了24例社会行为正常且接受低剂量治疗的患者。肌肉注射每周剂量为1.5毫克,持续使用6周,对1 - 5项精神症状、10项神经植物性症状和36项其他症状进行半定量评估。几乎所有症状都有显著改善,且未引起体重、血压值、脉搏频率变化,也未出现局部或全身不耐受情况。治疗病例的阳性结果达到77.3%,与众多国外作者报道的结果一致。

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