Pach J, Waniek W
Pharmakopsychiatr Neuropsychopharmakol. 1976 Mar;9(2):61-6. doi: 10.1055/s-0028-1094479.
Over a period of 8 weeks we compared the tranquilizing effects of the longterm neuroleptic Fluspirilene to those of Diazepam in a series of 28 patients. Both drugs showed good effects on somatization, anxiety and depressive mood. Fluspirilene, however, proved to be the more mood elevating and more activating agent without being hypnotic. The indications for both drugs are being discussed emphazising the new therapeutic perspectives of a long acting tranquilizer.
在8周的时间里,我们对28例患者进行了一系列研究,比较了长效抗精神病药氟斯必林与地西泮的镇静作用。两种药物对躯体化、焦虑和抑郁情绪均显示出良好疗效。然而,氟斯必林被证明是更能提升情绪和更具激活作用的药物,且无催眠作用。文中讨论了两种药物的适应证,强调了长效镇静剂的新治疗前景。