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新生儿结局:青少年怀孕是一个危险因素吗?

Neonatal outcome: is adolescent pregnancy a risk factor?

作者信息

Zuckerman B, Alpert J J, Dooling E, Hingson R, Kayne H, Morelock S, Oppenheimer E

出版信息

Pediatrics. 1983 Apr;71(4):489-93.

PMID:6835732
Abstract

It has been widely reported that adolescent mothers are more likely to experience poor pregnancy outcome, especially low-birth-weight and/or premature infants. Recent data suggest that this poor outcome may be attributed to confounding health and social characteristics of adolescent mothers. A study of maternal health and neonatal development at Boston City Hospital provided an opportunity to assess whether adolescent mothers deliver infants with poorer outcomes at birth than nonadolescents independent of numerous social and health differences between adolescent and nonadolescent mothers. A total of 275 infants of primiparous adolescents (aged 13 to 18 years) were compared at birth with 423 infants of primiparous nonadolescents. Size at birth, length of gestation, Apgar scores, and birth trauma were examined. The only statistically significant difference between the two groups was that adolescent mothers delivered infants whose mean weight was 94 g less (P less than .03) than infants of nonadolescent mothers. Multiple and logistic regression analyses demonstrated that several health and social factors, but not adolescent status, were independently associated with the measures of adverse infant outcome. A subsequent regression analysis demonstrated similarly that being a younger adolescent (16 years and younger) did not independently predict low birth weight at delivery or other measured adverse neonatal outcomes. These data support the view that health and social factors are more important to poor fetal outcome among primiparous mothers than adolescent status. Some of the health factors are amenable to clinical intervention.

摘要

据广泛报道,青少年母亲更易出现不良妊娠结局,尤其是低体重和/或早产婴儿。近期数据表明,这种不良结局可能归因于青少年母亲混杂的健康和社会特征。波士顿市医院一项关于孕产妇健康和新生儿发育的研究提供了一个机会,以评估青少年母亲分娩的婴儿在出生时的结局是否比非青少年母亲分娩的婴儿更差,而不考虑青少年母亲和非青少年母亲之间众多的社会和健康差异。将275名初产青少年(年龄13至18岁)的婴儿在出生时与423名初产非青少年的婴儿进行比较。检查了出生时的大小、妊娠时长、阿氏评分和出生创伤。两组之间唯一具有统计学意义的差异是,青少年母亲分娩的婴儿平均体重比非青少年母亲分娩的婴儿轻94克(P小于0.03)。多元和逻辑回归分析表明,几个健康和社会因素而非青少年身份与不良婴儿结局的指标独立相关。随后的回归分析同样表明,年龄较小的青少年(16岁及以下)并不能独立预测分娩时的低体重或其他测量的不良新生儿结局。这些数据支持这样一种观点,即对于初产母亲而言,健康和社会因素对不良胎儿结局比青少年身份更为重要。一些健康因素适合临床干预。

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