Mahoney W J, D'Souza B J, Haller J A, Rogers M C, Epstein M H, Freeman J M
Pediatrics. 1983 May;71(5):756-62.
Forty-six children with significant head trauma who remained in coma more than 24 hours were the subjects of this long-term outcome study. Twelve (38%) died. The average length of coma in the 34 survivors was 15.5 days. Follow-up ranged from 9 months to 4 years (mean 21 months). Twenty-nine percent of the survivors were normal at follow-up. An additional 53% had mild cognitive or behavioral problems, but 61% of these had evidence of similar problems prior to the injury. Nine percent of survivors had motor residua but normal intellect. Nine percent had severe intellectual and motor problems. Children less than 2 years of age had a worse outcome. Despite severe injury and prolonged coma after head trauma, most children do well. Intensive medical and surgical care increases the rate of survival and does not result in a large number of severely disabled survivors.
46名头部严重创伤且昏迷超过24小时的儿童是这项长期预后研究的对象。其中12名(38%)死亡。34名幸存者的平均昏迷时长为15.5天。随访时间从9个月至4年不等(平均21个月)。29%的幸存者在随访时情况正常。另有53%有轻度认知或行为问题,但其中61%在受伤前就有类似问题的迹象。9%的幸存者有运动后遗症但智力正常。9%有严重的智力和运动问题。2岁以下的儿童预后较差。尽管头部创伤后伤势严重且昏迷时间延长,但大多数儿童情况良好。强化医疗和外科护理提高了生存率,且不会导致大量严重残疾的幸存者。