Klonoff H, Clark C, Klonoff P S
Department of Psychiatry, University of British Columbia, Vancouver, Canada.
J Neurol Neurosurg Psychiatry. 1993 Apr;56(4):410-5. doi: 10.1136/jnnp.56.4.410.
The purpose of the 23 year follow up study was to determine the relationship between trauma variables including measures of head injury and very long-term sequelae. The study included 159 individuals with a mean age 31.40 years, of whom approximately 90% were admitted to hospital with a mild head injury during childhood (mean age 7.96). Extent of head injury was determined by unconsciousness, neurological status, skull fracture, EEG, post-traumatic seizures and a composite measure. The composite measure of neurological variables was the best predictor of long-term outcome. In addition, IQ recorded in the post-acute phase was a reliable predictor of long-term outcome. Of the sample, 32.7% reported physical complaints and 17.6% reported current psychological/psychiatric problems unrelated to the head injury. Subjective sequelae (physical, intellectual and emotional) specified as due to the head injury were reported by 31% of the sample, and the sequelae were found to be related to the extent of the head injury and initial IQ. There were no discernible relationships between attribute variables including premorbid status and age with subjective sequelae. There were, however, significant relationships between subjective sequelae and objective, psychosocial measures of adaptation including educational lag, unemployment, current psychological/psychiatric problems and relationships with family members. Finally, there appeared to be continuity of complaints elicited during the five year follow up of the original project and current sequelae. The severity of the head injury was identified as the primary contributory factor in the reconstitution process and in the prediction of long term outcomes.
这项为期23年的随访研究旨在确定包括头部损伤测量在内的创伤变量与非常长期后遗症之间的关系。该研究纳入了159名平均年龄为31.40岁的个体,其中约90%在童年时期(平均年龄7.96岁)因轻度头部损伤入院。头部损伤的程度由意识丧失、神经状态、颅骨骨折、脑电图、创伤后癫痫发作以及一项综合测量来确定。神经变量的综合测量是长期预后的最佳预测指标。此外,急性期后记录的智商是长期预后的可靠预测指标。在样本中,32.7%报告有身体不适,17.6%报告有与头部损伤无关的当前心理/精神问题。31%的样本报告了明确归因于头部损伤的主观后遗症(身体、智力和情感方面),并且发现这些后遗症与头部损伤的程度和初始智商有关。包括病前状态和年龄在内的属性变量与主观后遗症之间没有明显关系。然而,主观后遗症与客观的、社会心理适应指标之间存在显著关系,这些指标包括教育滞后、失业、当前心理/精神问题以及与家庭成员的关系。最后,在原始项目的五年随访期间引发的不适与当前后遗症之间似乎存在连续性。头部损伤的严重程度被确定为重建过程和长期预后预测中的主要促成因素。