Shepherd B A, Martan J
Prostate. 1983;4(2):215-21. doi: 10.1002/pros.2990040211.
Experiments were carried out to determine what factors are involved in the disappearance of stored secretion from the seminal vesicles of the guinea pig and in the concurrent decline in weight of these glands following castration. Seminal vesicles of sexually mature males were unilaterally ligated, and the males were either castrated or left testes intact for a 14-day period. At necropsy, the seminal vesicles were removed and weighed, and biopsies were collected for histological inspection. The weight of nonligated vesicles from castrated males declined to less than half that of ligated sides. In testes-intact males, the weight of ligated vesicles was nearly double that of nonligated vesicles. Epithelial cell heights remained unchanged during the study. The rapid decline in weight of the guinea pig seminal vesicles following castration was attributed to the elimination of stored secretion by way of the urethra rather than by absorption.
开展实验以确定哪些因素与豚鼠精囊储存分泌物的消失以及阉割后这些腺体重量的同时下降有关。对性成熟雄性豚鼠的精囊进行单侧结扎，然后将这些雄性豚鼠要么阉割，要么保留睾丸完整，为期14天。尸检时，取出精囊并称重，同时采集活检样本进行组织学检查。阉割雄性豚鼠未结扎侧精囊的重量降至结扎侧的一半以下。在保留睾丸的雄性豚鼠中，结扎侧精囊的重量几乎是非结扎侧的两倍。在研究过程中，上皮细胞高度保持不变。豚鼠阉割后精囊重量的快速下降归因于通过尿道而非吸收来消除储存的分泌物。
