Kräuchi K, Wirz-Justice A, Willener R, Campbell I C, Feer H
Physiol Behav. 1983 Jan;30(1):35-40. doi: 10.1016/0031-9384(83)90035-5.
Baseline and reactive motor activity and corticosterone levels of spontaneous hypertensive rats (SHR) and their normotensive controls (WKY) were compared with respect to circadian rhythmicity. In the open field, SHR showed higher ambulation and rearing and less defecation than WKY in both light and dark phases. There were significant interactions between strain and time of day in the rate of habituation. SHR showed elevated baseline motor activity, increased motor response and enhanced corticosterone response to "mild" stress only in the light phase. There may be a disorder of temporal organisation in SHR characterised by increased sensitivity to external stimuli during the sleeping state.
比较了自发性高血压大鼠（SHR）及其正常血压对照大鼠（WKY）的基线和反应性运动活动以及皮质酮水平的昼夜节律性。在旷场实验中，SHR在光照和黑暗阶段的行走和竖毛行为均比WKY多，排便则比WKY少。在习惯化速率方面，品系和时间之间存在显著的交互作用。SHR仅在光照阶段表现出基线运动活动增加、运动反应增强以及对“轻度”应激的皮质酮反应增强。SHR可能存在时间组织紊乱，其特征是在睡眠状态下对外部刺激的敏感性增加。
