Dunnick N R, Hartman D S, Ford K K, Davis C J, Amis E S
Radiology. 1983 May;147(2):321-6. doi: 10.1148/radiology.147.2.6836111.
Nine cases of proven juxtaglomerular tumor of the kidney are reviewed. Each patient presented with hypertension; elevated peripheral renin levels were found in four patients. As in past studies, this tumor occurred more frequently in women (7/9 cases). Although the patients tended to be younger (mean age, 31 years) than those with essential hypertension, all but two patients were more than 20 years of age. In all cases, the tumor was solitary, well-defined, and curable by surgery. The tumor was identified by excretory urography in 5/8 patients who underwent this procedure. A solid renal mass was detected in each of the seven patients examined by ultrasound. Since the tumor tends to be isodense with normal renal parenchyma, it is sometimes not seen on computed tomography without intravenous contrast material. Arteriography revealed a hypovascular mass in each of the nine patients. The combination of a hypovascular solid renal mass in a patient with elevated renin but no renal artery lesions should suggest the diagnosis of a juxtaglomerular cell tumor.
回顾了9例经证实的肾球旁细胞瘤病例。每位患者均表现为高血压;4例患者外周肾素水平升高。与以往研究一样,该肿瘤在女性中更为常见(7/9例)。尽管患者往往比原发性高血压患者更年轻(平均年龄31岁),但除2例患者外,所有患者年龄均超过20岁。在所有病例中,肿瘤均为单发,边界清晰,可通过手术治愈。在接受排泄性尿路造影的8例患者中,有5例通过该检查发现了肿瘤。7例接受超声检查的患者均检测到实性肾肿块。由于肿瘤往往与正常肾实质等密度,因此在未使用静脉造影剂的计算机断层扫描中有时看不到。血管造影显示9例患者中的每例均有少血管肿块。对于肾素升高但无肾动脉病变的患者,出现少血管实性肾肿块应提示诊断为肾球旁细胞瘤。