Maurus J N
Obstet Gynecol. 1978 Jul;52(1):22-5.
Hansen's disease with pregnancy is an uncommon concurrence in the United States. The clinical courses of 62 pregnancies in 26 treated patients with various types of Hansen's disease are reported. In general, patients with Hansen's disease do well in pregnancy. However, the subgroups of active lepromatous and dimorphous types have an increased incidence of obstetric and disease complications. Additional important observations include a high incidence of false-positive biologic tests for syphilis, with the possibility that the FTA-ABS test may also be falsely positive in pregnant patients with Hansen's disease. Sulfone drugs may be used safely during pregnancy. There is a low incidence of congenital malformations, but an unusually high incidence of twinning in this small group of patients.
在美国，妊娠合并麻风病是一种罕见的情况。本文报告了26例接受治疗的不同类型麻风病患者的62次妊娠的临床过程。总体而言，麻风病患者在孕期情况良好。然而，活动性瘤型和混合型亚组的产科及疾病并发症发生率有所增加。其他重要观察结果包括梅毒生物学检测假阳性率高，且在妊娠合并麻风病患者中荧光螺旋体抗体吸收试验（FTA - ABS）也可能出现假阳性。砜类药物在孕期可安全使用。先天性畸形发生率低，但在这一小群患者中双胎发生率异常高。
