BB/W大鼠糖尿病的被动转移
Passive transfer of diabetes in the BB/W rat.
作者信息
Koevary S, Rossini A, Stoller W, Chick W, Williams R M
出版信息
Science. 1983 May 13;220(4598):727-8. doi: 10.1126/science.6836309.
PMID:6836309
Abstract
Severe diabetes with insulitis was produced in young diabetes-prone BB/W rats by passive transfer of concanavalin A-treated spleen cells from BB/W animals with acute diabetes. Spleen cells alone or in combination with lymph node cells were active in transferring disease.
摘要
通过被动转移来自患有急性糖尿病的BB/W动物的伴刀豆球蛋白A处理的脾细胞，在易患糖尿病的年轻BB/W大鼠中诱发了伴有胰岛炎的严重糖尿病。单独的脾细胞或与淋巴结细胞联合使用时，在转移疾病方面具有活性。
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