[Changes in the content and concentration of cytoplasmic and nuclear proteins in nerve and glial cells of hypothalamic nuclei at different times of water deprivation].

The data obtained show that searching activity of animals increases at an early stage (24 hrs) of water deprivation (WD) and is accompanied by an increase in the content of cytoplasmic proteins. WD up to 3 days produces further rise of motor searching activity with simultaneous increase of protein content not in the cytoplasm alone but in the nuclei of neurons and glial cells as well. During long-term periods of WD (5 days), motor activity considerably decreases, the animals showing signs of depression. The content and concentration of proteins significantly decrease in all studied components of neurons and glia of the hypothalamic nuclei under study. Existence of correlation between protein content (cytoplasmic and nuclear) and behavior of animals is discussed.