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[冷适应过程中大鼠下丘脑神经元细胞核和神经胶质细胞核中酸性蛋白的浓度]

[Concentration of acid proteins in the nuclei of rat hypothalamic neuron and glial cell nuclei during cold adaptation].

作者信息

Mogil'nitskaia L V, Pevzner L Z

出版信息

Biull Eksp Biol Med. 1978 Aug;86(8):187-90.

PMID:687814
Abstract

By means of two-wave length cytospectrophotometry the acid protein content per cell was determined in the nuclei of the neurons and their glial satellite cells of the medial peroptic area and the supraoptic nucleus of the hypothalamus of rats kept at 2--4 degrees C for 1, 3, 7, or 15 days (adaptation to cold). This colling resulted in an initial decrease in the nuclear acid protein content in the whole neuron-neuroglia system of the medail preoptic area with a gradual restoration to the normal by the 15th day of constant cooling. In the glial cells of this area the acid protein content increased temporarily above the control level before the restoration to the normal. A gradual accumulation of acid proteins and its following restoration to the control level was revealed in the neuron-neuroglia system of the supraoptic nucleus. By the 15th day of the adaptation to cold the content of neuronal and glial acid proteins of this nucleus became somewhat lower than in the control.

摘要

采用双波长细胞分光光度法,测定了在2 - 4摄氏度下饲养1、3、7或15天(冷适应)的大鼠下丘脑视前内侧区和视上核神经元及其神经胶质卫星细胞核中每个细胞的酸性蛋白质含量。这种低温导致视前内侧区整个神经元 - 神经胶质系统中核酸蛋白质含量最初下降,在持续低温的第15天逐渐恢复正常。在该区域的神经胶质细胞中,酸性蛋白质含量在恢复正常之前暂时高于对照水平。视上核的神经元 - 神经胶质系统中发现酸性蛋白质逐渐积累,随后恢复到对照水平。到冷适应的第15天,该核中神经元和神经胶质酸性蛋白质的含量比对照略低。

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