Klimenko E M, Sheveleva V S, Mel'nikov R A
Vopr Onkol. 1983;29(2):19-25.
The levels of catecholamines (adrenaline, noradrenaline, dopamine) in gastrointestinal tumors and normal tissue adjacent to malignant tumor were studied. Noradrenaline level in tumor was considerably lower than that in normal tissue. Neither adrenaline nor dopamine level showed any changes. It was established that tumor development occurs against the background of functional desympathization and adverse changes in the ratio of mediator and hormonal links in tissue sympatho-adrenal system.
研究了胃肠道肿瘤及恶性肿瘤旁正常组织中儿茶酚胺(肾上腺素、去甲肾上腺素、多巴胺)的水平。肿瘤中去甲肾上腺素水平显著低于正常组织。肾上腺素和多巴胺水平均未显示出任何变化。已确定肿瘤的发展是在功能去交感神经化以及组织交感 - 肾上腺系统中介质和激素联系比例发生不利变化的背景下发生的。