Zubareva T V, Kiseleva Z M
Ophthalmologica. 1977;175(6):339-44. doi: 10.1159/000308678.
The level of catecholamines was determined in the lacrimal fluid since it may serve as an index of the activity of the sympatho-adrenal system. 86 persons aged between 35 and 65 years were studied. Of these, 49 were glaucoma patients, 16 patients had preglaucoma, and 21 practically healthy subjects served as a control. The results of the study showed that dopa and catecholamines: dopamine, noradrenaline and adrenaline can be determined in the lacrimal fluid of healthy people. Preglaucoma patients were found to have a reduced level of dopamine and its precursor dopa. Glaucoma patients were found to have reduced levels of dopa and noradrenaline. Determination of the level of catecholamine and dopa is considered to be an immediate index of the state of the sympathoadrenal system in the initial glaucoma. Determination of catecholamines and dopa in the lacrimal fluid can serve as a test in glaucoma diagnosis.
由于泪液中的儿茶酚胺水平可作为交感 - 肾上腺系统活动的指标，因此对其进行了测定。研究对象为86名年龄在35至65岁之间的人。其中，49名是青光眼患者，16名是青光眼前期患者，21名身体健康的受试者作为对照组。研究结果表明，在健康人的泪液中可以检测到多巴和儿茶酚胺：多巴胺、去甲肾上腺素和肾上腺素。青光眼前期患者的多巴胺及其前体多巴水平降低。青光眼患者的多巴和去甲肾上腺素水平降低。儿茶酚胺和多巴水平的测定被认为是原发性青光眼交感肾上腺系统状态的直接指标。泪液中儿茶酚胺和多巴的测定可作为青光眼诊断的一项检测。
