Hylander E, Jarnum S, Nielsen K
Scand J Gastroenterol. 1980;15(3):349-52. doi: 10.3109/00365528009181482.
The effect of oral calcium on oxalate absorption was studied in eight patients with secondary hyperoxaluria after jejunoileal bypass for morbid obesity during a standardized diet with a fixed supply of fat, calcium, and oxalate. A supplementary calcium dose of 2000 mg/day reduced renal oxalate excretion from 119 to 60 mg/24 h (median values, p < 0.01). Correspondingly, 14C-oxalate absorption decreased from 28% to 9% (p < 0.01). No statistically significant increase in urinary calcium was observed. The study shows that renal oxalate excretion in patients with enteric hyperoxaluria can be reduced by oral calcium. However, we doubt that it has any practical, clinical importance.
在一项针对八名病态肥胖患者进行空肠回肠旁路手术后继发高草酸尿症的研究中，研究人员在固定供应脂肪、钙和草酸盐的标准化饮食条件下，探讨了口服钙对草酸盐吸收的影响。每天补充2000毫克钙可使肾草酸盐排泄量从119毫克/24小时降至60毫克/24小时（中位数，p<0.01）。相应地，14C-草酸盐吸收从28%降至9%（p<0.01）。未观察到尿钙有统计学意义的增加。该研究表明，口服钙可降低肠道高草酸尿症患者的肾草酸盐排泄。然而，我们怀疑其是否具有任何实际的临床重要性。
