Uchibori N, Yoshizaki S, Shamoto M, Takeuchi J
Acta Pathol Jpn. 1983 Jan;33(1):141-6. doi: 10.1111/j.1440-1827.1983.tb02106.x.
A case of an epidermoid carcinoma which arose in a cystic adenolymphoma-like lesion of the parotid gland is presented. Histologically, in the major part, the tumor tissue showed a papillary cystadenoma lymphomatosum-like pattern with the stroma consisting of mainly plasma cells and lymphocytes, but the epithelial element was mostly multilayered, showing a keratinous differentiation. In some areas, sebaceous-like cells and oxyphilic cells were found in the epithelial component. In the surrounding fibrous tissue, the invasive growth of the epithelial cells could be observed. Microdeposit of amyloid substance was found in the lymphoid stromal tissue and also in the intercellular space of the epithelial element. A mass of epithelioid cells and cholesterol crystal clefts were observed in the granulomatous tissue which proliferated around the tumor tissues. About 4 months after surgical excision, a recurrent tumor, which was well differentiated squamous cell carcinoma, appeared on the same site as the primary tumor.
本文报告1例发生于腮腺囊性腺淋巴瘤样病变中的表皮样癌。组织学上，大部分肿瘤组织呈淋巴乳头状囊腺瘤样结构，间质主要由浆细胞和淋巴细胞组成，但上皮成分大多为多层，显示角质分化。在某些区域，上皮成分中可见皮脂腺样细胞和嗜酸性细胞。在周围纤维组织中，可观察到上皮细胞的浸润性生长。在淋巴间质组织以及上皮成分的细胞间隙中发现有淀粉样物质微沉积。在肿瘤组织周围增生的肉芽肿组织中观察到大量上皮样细胞和胆固醇结晶裂隙。手术切除约4个月后，在原发肿瘤相同部位出现复发肿瘤，为高分化鳞状细胞癌。
