痤疮丙酸杆菌临床分离株对22种抗菌药物的敏感性
Susceptibility of Propionibacterium acnes clinical isolates to 22 antimicrobial agents.
作者信息
Denys G A, Jerris R C, Swenson J M, Thornsberry C
出版信息
Antimicrob Agents Chemother. 1983 Feb;23(2):335-7. doi: 10.1128/AAC.23.2.335.
Abstract
Susceptibilities of 104 Propionibacterium acnes isolates to each of 22 antimicrobial agents was evaluated by broth microdilution. These isolates were susceptible to all of the test agents except metronidazole. N-Formimidoyl thienamycin, a penem coded Sch 29482, and penicillin ranked first, second, and third, respectively, in activity and were significantly more active than other penicillins, cephalosporins, tetracyclines, clindamycin, or chloramphenicol.
摘要
通过肉汤微量稀释法评估了104株痤疮丙酸杆菌分离株对22种抗菌药物的敏感性。这些分离株对除甲硝唑外的所有测试药物均敏感。N-甲酰亚胺基硫霉素（一种名为Sch 29482的青霉烯类药物）、青霉素在活性方面分别排名第一、第二和第三，且其活性显著高于其他青霉素、头孢菌素、四环素、克林霉素或氯霉素。
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