痤疮丙酸杆菌及相关微生物种类的抗菌药敏性。
Antimicrobiol susceptibility of Propinibacterium acnes and related microbial species.
作者信息
Hoeffler U, Ko H L, Pulverer G
出版信息
Antimicrob Agents Chemother. 1976 Sep;10(3):387-94. doi: 10.1128/AAC.10.3.387.
Abstract
The minimal inhibitory concentrations of 32 antimicrobial agents were established for 73 strains of Propionibacterium acnes and four related species (P. granulosum, P. avidum, Corynebacterium minutissimum, and C. parvum). Most strains showed good susceptibility to those agents usually considered active against gram-positive organisms. With the exception of C. minutissimum, the strains tested revealed more or less identical susceptibility ranges. The lowest minimal inhibitory concentrations were observed with benzylpenicillin, ampicillin, cephalothin, rifampin, erythromycin, clindamycin, and minocycline. C. minutissimum was more susceptible to gentamicin, sisomicin, tobramycin, and fusidic acid but more resistant to most other drugs than were the other species examined.
摘要
测定了32种抗菌剂对73株痤疮丙酸杆菌及4种相关菌（颗粒丙酸杆菌、嗜丙酸丙酸杆菌、极小棒状杆菌和短小棒状杆菌）的最低抑菌浓度。大多数菌株对通常认为对革兰氏阳性菌有效的抗菌剂表现出良好的敏感性。除极小棒状杆菌外，所测试的菌株显示出或多或少相同的敏感范围。苄青霉素、氨苄青霉素、头孢噻吩、利福平、红霉素、克林霉素和米诺环素的最低抑菌浓度最低。与其他所检测的菌种相比，极小棒状杆菌对庆大霉素、西索米星、妥布霉素和夫西地酸更敏感，但对大多数其他药物更耐药。
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