Zelenetskaia V S, Dobracheva A D, Pishchulin A A, Zheldak L V, Razmadze T G
Probl Endokrinol (Mosk). 1978 Jul-Aug;24(4):36-41.
The authors studied the content of gonadotropins and testosterone in the blood; functional condition of the hypothalamus-hypophysis-ovarian system was characterized in patients with ovarian hyperandrogenia by using the klomiphen test. Testosterone level in all the patients and prolactin level in 70% of the patients proved to exceed the normal values, wheras the LH level could be low, normal or high. With klomiphen test it was shown that both the gonadotropin and estrogen levels rose against the background of action of the preparation; as to testosterone level--it remained unchanged. In induced menstrual cycles estradiol peak preceded the gonadotropin peak. In patients with ovulation testosterone level diminished by the end of the observation period.
作者研究了血液中促性腺激素和睾酮的含量；通过克罗米酚试验对卵巢雄激素过多患者下丘脑-垂体-卵巢系统的功能状态进行了表征。所有患者的睾酮水平以及70%患者的催乳素水平均超过正常值，而促黄体生成素（LH）水平可能低、正常或高。通过克罗米酚试验表明，在该制剂作用的背景下，促性腺激素和雌激素水平均升高；至于睾酮水平——保持不变。在诱导的月经周期中，雌二醇峰值先于促性腺激素峰值出现。在有排卵的患者中，观察期末睾酮水平降低。
