Scaglia H, Medina M, Gual C, Cabeza M, Pérez-Palacios G
Fertil Steril. 1976 Mar;27(3):243-9.
Hypothalamic and pituitary gonadotropin function and responsiveness in four patients with well-documented Stein-Leventhal syndrome were studied. All patients were of reproductive age and had had menstrual disorders since menarche. Estrogen production was assessed by measuring the circulating levels of immunoreactive estradiol, by vaginal smears, and by the progestogen-induced menses test. Gonadotropin function was evaluated by measuring the serum levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in blood samples obtained at 15-minute intervals for 150 minutes. Pituitary gonadotropin reserve and responsiveness were studied by giving an intravenous bolus of synthetic LH-releasing hormone (LH-RH) and measuring the circulating gonadotropin levels before and after the injection.
对四名确诊为斯坦因-莱文塔尔综合征的患者的下丘脑和垂体促性腺激素功能及反应性进行了研究。所有患者均处于生育年龄，自初潮起即有月经紊乱。通过测量循环中免疫反应性雌二醇水平、阴道涂片以及孕激素诱导月经试验来评估雌激素生成。通过在150分钟内每隔15分钟采集血样，测量血清黄体生成素（LH）和卵泡刺激素（FSH）水平来评估促性腺激素功能。通过静脉推注合成促黄体生成素释放激素（LH-RH）并测量注射前后循环促性腺激素水平，研究垂体促性腺激素储备和反应性。
